circRNA basic information
circBase ID: -
Name: hsa_circ_PITX1
Synonym: -
Host Gene: hsa-miR-584-5p
 
 
 
Disease basic information
DO ID:
 3073
DO name: brain glioblastoma multiforme
Disease details: glioblastoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: SHG-44, U251
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: KPNB1
Associated microRNA: hsa-miR-584-5p
Biological function: knockdown of circPITX1 suppressed proliferation, angiogenesis, migration, invasion, and tumor growth in vivo along with induced cell cycle arrest of GBM cells
Molecular mechanism: circPITX1/hsa-miR-584-5p/KPNB1 axis
Survival: -
Supported No.:
 3
Description:

circPITX1/miR-584-5p/KPNB1 axis regulated GBM process via mediating proliferation, angiogenesis, migration, invasion, and cell cycle process of GBM cells.
Other information
Title:

CircPITX1 Regulates Proliferation, Angiogenesis, Migration, Invasion, and Cell Cycle of Human Glioblastoma Cells by Targeting miR-584-5p/KPNB1 Axis.

Journal: J Mol Neurosci
Published: 2021/3/26
PubMed ID: 33763840