circRNA basic information
circBase ID: hsa_circ_0072309
Name: hsa_circ_LIFR
Synonym: -
Host Gene: -
 
 
 
Disease basic information
DO ID:
 10534
DO name: stomach cancer
Disease details: gastric cancer
Species: human
Species details: human
Sample type: cell line
Sample type details: AGS, MKN-45
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: PI3K/AKT signaling and the PPARgamma/PTEN
Associated microRNA: -
Biological function: inhibits the proliferation, invasion and migration
Molecular mechanism: via inhibition of PI3K/AKT signaling by activating PPARgamma/PTEN signaling
Survival: -
Supported No.:
 2
Description:

hsa_circ_0072309 inhibited proliferation, invasion and migration of gastric cancer cells via the inhibition of PI3K/AKT signaling by activating the PPARgamma/PTEN signaling pathway. Targeting hsa_circ_0072309 may be an innovative therapeutic strategy for the treatment of GC.
Other information
Title:

Circular RNA hsa_circ_0072309 inhibits the proliferation, invasion and migration of gastric cancer cells via inhibition of PI3K/AKT signaling by activating PPARgamma/PTEN signaling.

Journal: Mol Med Rep
Published: 2021/3/25
PubMed ID: 33760104