circRNA basic information
circBase ID: -
Name: hsa_circ_SEC24A
Synonym: -
Host Gene: hsa-miR-142-5p
 
 
 
Disease basic information
DO ID:
 8398
DO name: osteoarthritis
Disease details: osteoarthritis
Species: human
Species details: human
Sample type: tissue
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: SOX5
Associated microRNA: hsa-miR-142-5p
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 3
Description:

CircSEC24A aggravated IL-1beta-induced injury via modulating miR-142-5p/SOX5 axis, providing possible targets for the clinical diagnosis and treatment of OA.
Other information
Title:

CircSEC24A promotes IL-1beta-induced apoptosis and inflammation in chondrocytes by regulating miR-142-5p/SOX5 axis.

Journal: Biotechnol Appl Biochem
Published: 2021/3/23
PubMed ID: 33751650