circRNA basic information
circBase ID: -
Name: hsa_circ_SMARCA5
Synonym: -
Host Gene: hsa-miR-552
 
 
 
Disease basic information
DO ID:
 219
DO name: colon cancer
Disease details: colon cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: SW480, SW620
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-552
Biological function: Transfection with overexpressing circSMARCA5 plasmid restrained growth, migration and invasion of colon cancer cells
Molecular mechanism: circSMARCA5 directly sponged to hsa-miR-552 and hsa-miR-552 up-regulation offset the effects of circSMARCA5
Survival: -
Supported No.:
 1
Description:

circSMARCA5 inactivated Wnt and YAP1 pathways by inhibiting miR-552. Anti-tumor role of sircSMARCA5 was showed in colon cancer cells as sponging miR-552 and blocking Wnt and YAP1 pathways.
Other information
Title:

Circular RNA SMARCA5 functions as an anti-tumor candidate in colon cancer by sponging microRNA-552.

Journal: Cell Cycle
Published: 2021/3/23
PubMed ID: 33749508