circRNA basic information
circBase ID: hsa_circ_0005774
Name: -
Synonym: circ_0005774
Host Gene: hsa-miR-192-5p
 
 
 
Disease basic information
DO ID:
 9119
DO name: acute myeloid leukemia
Disease details: acute myeloid leukemia
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: HL-60 (ACC-3), NB4 (ACC-207)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: ULK1
Associated microRNA: hsa-miR-192-5p
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 1
Description:

circ_0005774 knockdown repressed cell proliferation and promoted apoptosis of AML cells partially through regulating miR-192-5p/ULK1 axis.
Other information
Title:

Circular RNA circ_0005774 contributes to proliferation and suppresses apoptosis of acute myeloid leukemia cells via circ_0005774/miR-192-5p/ULK1 ceRNA pathway.

Journal: Biochem Biophys Res Commun
Published: 2021/3/19
PubMed ID: 33735626