circRNA basic information
circBase ID: hsa_circ_0005927
Name: -
Synonym: circ_0005927
Host Gene: hsa-miR-942-5p
 
 
 
Disease basic information
DO ID:
 9256
DO name: colorectal cancer
Disease details: colorectal cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: SW620, SW480, Caco-2, LoVo
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: BATF2
Associated microRNA: hsa-miR-942-5p
Biological function: Circ_0005927 overexpression repressed cell colony-forming ability, migration and invasion, whereas induced cell apoptosis in CRC
Molecular mechanism: circ_0005927 was a sponge of hsa-miR-942-5p, and hsa-miR-942-5p bound to BATF2
Survival: -
Supported No.:
 2
Description:

Circ_0005927 suppressed cell colony-forming ability, migration and invasion, and promoted cell apoptosis by sponging miR-942-5p to induce BATF2 in CRC. The possible mechanism provides a theoretical basis for the study of circRNA-directed therapy for CRC.
Other information
Title:

Circ_0005927 Inhibits the Progression of Colorectal Cancer by Regulating miR-942-5p/BATF2 Axis.

Journal: Cancer Manag Res
Published: 2021/3/19
PubMed ID: 33732022