circRNA basic information
circBase ID: hsa_circ_0087378
Name: hsa_circ_NTRK2
Synonym: -
Host Gene: hsa-miR-140-3p
 
 
 
Disease basic information
DO ID:
 3748
DO name: esophagus squamous cell carcinoma
Disease details: esophageal squamous cell carcinoma
Species: human
Species details: human
Sample type: tissue
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: E2F3
Associated microRNA: hsa-miR-140-3p
Biological function: promote the proliferation, migration, and invasion
Molecular mechanism: upregulating E2F3 expression
Survival: poor
Supported No.:
 2
Description:

circ_0087378 might act as a competing endogenous RNA for miR-140-3p, which could inhibit the tumorigenesis and progression of ESCC through upregulating E2F3 expression.
Other information
Title:

Knockdown of circRNA circ_0087378 Represses the Tumorigenesis and Progression of Esophageal Squamous Cell Carcinoma Through Modulating the miR-140-3p/E2F3 Axis.

Journal: Front Oncol
Published: 2021/3/9
PubMed ID: 33680929