circRNA basic information
circBase ID: hsa_circ_0099198
Name: hsa_circ_TRHDE
Synonym: -
Host Gene: hsa-miR-1287
 
 
 
Disease basic information
DO ID:
 768
DO name: retinoblastoma
Disease details: retinoblastoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: Y79, Weri-Rb-1
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: LRP6
Associated microRNA: hsa-miR-1287
Biological function: circ_0099198 silencing suppressed proliferation and metastasis and expedited cell cycle arrest and apoptosis
Molecular mechanism: regulating hsa-miR-1287/LRP6 axis
Survival: -
Supported No.:
 1
Description:

circ_0099198 contributed to RB progression by sponging miR-1287 and up-regulating LRP6, which provided novel biomarkers for RB therapy.
Other information
Title:

Hsa_circ_0099198 facilitates the progression of retinoblastoma by regulating miR-1287/LRP6 axis.

Journal: Exp Eye Res
Published: 2021/3/8
PubMed ID: 33676964