circRNA basic information
circBase ID: hsa_circ_0021093
Name: -
Synonym: circ_0021093
Host Gene: hsa-miR-432
 
 
 
Disease basic information
DO ID:
 684
DO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: SNU-449, HCCLM3, Huh-7, FHCC-98
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: ANXA2
Associated microRNA: hsa-miR-432
Biological function: knockdown of circ_0021093 repressed proliferation, migration and invasion in vitro and tumor growth in vivo
Molecular mechanism: regulating hsa-miR-432
Survival: poor
Supported No.:
 2
Description:

circ_0021093 boosted HCC progression via regulating proliferation, migration and invasion of HCC cells by acting as competing endogenous RNA to sponge miR-432.
Other information
Title:

Circular RNA circ_0021093 regulates miR-432/Annexin A2 pathway to promote hepatocellular carcinoma progression.

Journal: Anticancer Drugs
Published: 2021/3/7
PubMed ID: 33675609