circRNA basic information
circBase ID: -
Name: hsa_circ_LAMP1
Synonym: -
Host Gene: hsa-miR-556-5p, hsa-miR-567
 
 
 
Disease basic information
DO ID:
 4947
DO name: cholangiocarcinoma
Disease details: cholangiocarcinoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: Huh_28, QBC939, HuCCT1, CCLP1
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: YY1
Associated microRNA: hsa-miR-556-5p, hsa-miR-567
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 1
Description:

circ-LAMP1 directly sponged miR-556-5p and miR-567, thereby releasing their suppression on YY1 at post-transcriptional level. Rescue assay indicated that the oncogenic role of circ-LAMP1 is partially dependent on its modulation of YY1 in CCA.
Other information
Title:

Circ-LAMP1 contributes to the growth and metastasis of cholangiocarcinoma via miR-556-5p and miR-567 mediated YY1 activation.

Journal: J Cell Mol Med
Published: 2021/3/7
PubMed ID: 33675150