circRNA basic information
circBase ID: -
Name: hsa_circ_ROBO2
Synonym: -
Host Gene: hsa-miR-1184
 
 
 
Disease basic information
DO ID:
9408
DO name: acute myocardial infarction
Disease details: acute myocardial Infarction
Species: human
Species details: human
Sample type: tissue
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: TRADD
Associated microRNA: hsa-miR-1184
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
1
Description:

Knockdown of circROBO2 reduced the apoptosis of cardiomyocytes by increasing the expression levels of miR-1184, which in turn decreased the expression levels of TRADD in the myocardium post-MI.

Other information
Title:

Knockdown of circROBO2 attenuates acute myocardial infarction through regulating the miR-1184/TRADD axis.

Journal: Mol Med
Published: 2021/3/5
PubMed ID: 33658002