circRNA basic information
circBase ID: -
Name: hsa_circ_GLIS3
Synonym: -
Host Gene: hsa-miR-1273f
 
 
 
Disease basic information
DO ID:
 11054
DO name: urinary bladder cancer
Disease details: bladder cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: T24, UM-UC-3
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: SKP1/Cyclin D1
Associated microRNA: hsa-miR-1273f
Biological function: -
Molecular mechanism: upregulates the expression of SKP1 by adsorbing hsa-miR-1273f and then promotes cyclin D1 expression
Survival: -
Supported No.:
 1
Description:

circGLIS3 upregulates the expression of SKP1 by adsorbing miR-1273f and then promotes cyclin D1 expression, ultimately promoting the proliferation of bladder cancer cells. In summary, our study indicates that circGLIS3 plays an oncogene role in the development of bladder cancer and has potential to be a candidate for bladder cancer.
Other information
Title:

Circular RNA circGLIS3 promotes bladder cancer proliferation via the miR-1273f/SKP1/Cyclin D1 axis.

Journal: Cell Biol Toxicol
Published: 2021/3/4
PubMed ID: 33656636