circRNA basic information
circBase ID: -
Name: hsa_circ_SPATA6
Synonym: -
Host Gene: hsa-miR-182
 
 
 
Disease basic information
DO ID:
 50866
DO name: oral squamous cell carcinoma
Disease details: oral squamous cell carcinoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: CAL-27, SCC9
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: TRAF6
Associated microRNA: hsa-miR-182
Biological function: circSPATA6 impeded migration and invasion, and facilitated cell cycle arrest and apoptosis of OSCC cells
Molecular mechanism: circSPATA6 could modulate TRAF6 expression through sponging hsa-miR-182
Survival: -
Supported No.:
 1
Description:

CircSPATA6 curbed migration and invasion, and expedited cell cycle arrest and apoptosis in OSCC cells partly through regulating the miR-182/TRAF6 axis. These findings hinted at an underlying circRNA-targeted therapy for OSCC.
Other information
Title:

Circular RNA circSPATA6 Inhibits the Progression of Oral Squamous Cell Carcinoma Cells by Regulating TRAF6 via miR-182.

Journal: Cancer Manag Res
Published: 2021/3/4
PubMed ID: 33654430