circRNA basic information
circBase ID: hsa_circ_0000212
Name: -
Synonym: circ-0000212
Host Gene: hsa-miR-491
 
 
 
Disease basic information
DO ID:
 9256
DO name: colorectal cancer
Disease details: colorectal cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: SW620, SW480, LoVo, HT29, HCT116
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: FOXP4
Associated microRNA: hsa-miR-491
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 1
Description:

miR_491 inhibited cell proliferation by targeting FOXP4. circ_0000212 was increased in CRC tissues and was predominantly localized in the cytoplasm. Furthermore, circ_0000212 augmented viability of the CRC cells by sponging miR_491 and modulating FOXP4.

Other information
Title:

circ_0000212 promotes cell proliferation of colorectal cancer by sponging miR_491 and modulating FOXP4 expression.

Journal: Mol Med Rep
Published: 2021/3/3
PubMed ID: 33649850