circRNA basic information
circBase ID: hsa_circ_0000003
Name: -
Synonym: circ_0000003
Host Gene: hsa-miR-330-3p
 
 
 
Disease basic information
DO ID:
 50865
DO name: tongue squamous cell carcinoma
Disease details: tongue squamous cell carcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: SCC25, SCC4, Cal27, SCC1
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: GLS
Associated microRNA: hsa-miR-330-3p
Biological function: Circ_0000003 was revealed to facilitate cell proliferation, migration and invasion of TSCC cells
Molecular mechanism: acted as a competing endogenous RNA (ceRNA) that sponged miR_330_3p, thereby elevating glutaminase (GLS) expression
Survival: poor
Supported No.:
 1
Description:

circ_0000003 facilitates TSCC cell proliferation, migration, invasion and glutamine catabolism by regulating the miR_330_3p/GLS pathway.
Other information
Title:

Circ_0000003 regulates glutamine metabolism and tumor progression of tongue squamous cell carcinoma via the miR_330_3p/GLS axis.

Journal: Oncol Rep
Published: 2021/3/3
PubMed ID: 33649795