circRNA basic information
circBase ID: -
Name: hsa_circ_AGAP1
Synonym: circ0058792
Host Gene: hsa-miR-15-5p
 
 
 
Disease basic information
DO ID:
 4467
DO name: clear cell renal cell carcinoma
Disease details: clear cell renal cell carcinoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: ACHN, A498
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
UP
Associated gene: E2F3
Associated microRNA: hsa-miR-15-5p
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 1
Description:

Our results clarify that circAGAP1 exerts its oncogenic functions as a competitive endogenous RNA (ceRNA) by sponging miR-15-5p, which promotes E2F3 expression. Targeting circAGAP1 might be a new attractive therapeutic strategy in ccRCC.
Other information
Title:

CircAGAP1 promotes tumor progression by sponging miR-15-5p in clear cell renal cell carcinoma.

Journal: J Exp Clin Cancer Res
Published: 2021/2/24
PubMed ID: 33618745