circRNA basic information
circBase ID: -
Name: hsa_circ_GDI2
Synonym: -
Host Gene: hsa-miR-454-3p
 
 
 
Disease basic information
DO ID:
 50866
DO name: oral squamous cell carcinoma
Disease details: oral squamous cell carcinoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: SCC-15, HSC-3
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: FOXF2
Associated microRNA: hsa-miR-454-3p
Biological function: CircGDI2 overexpression could effectively inhibit the proliferation, migration, invasion and promote apoptosis in OSCC cells, and suppress OSCC tumor growth in nude mice in vivo
Molecular mechanism: via hsa-miR-454-3p/FOXF2 axis
Survival: -
Supported No.:
 2
Description:

CircGDI2 served as a repressor to restrain OSCC malignancy via miR-454-3p/FOXF2 axis, which might be a novel biomarker for targeted OSCC therapy.
Other information
Title:

CircGDI2 Regulates the Proliferation, Migration, Invasion and Apoptosis of OSCC via miR-454-3p/FOXF2 Axis.

Journal: Cancer Manag Res
Published: 2021/2/20
PubMed ID: 33603482