circRNA basic information
circBase ID: hsa_circ_0101187
Name: hsa_circ_YY1
Synonym: -
Host Gene: hsa-miR-769-3p
 
 
 
Disease basic information
DO ID:
 1612
DO name: breast cancer
Disease details: breast cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: MCF7, BT549, MDA-MB-231, MDA-MB-468, T47D
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: YY1
Associated microRNA: hsa-miR-769-3p
Biological function: Both circYY1 inhibition and miR-769-3p elevation constrained BC cell viability, colony formation, migration, invasion, and glycolysis in vitro
Molecular mechanism: sponged hsa-miR-769-3p to modulate YY1 expression
Survival: -
Supported No.:
 1
Description:

CircYY1 promoted glycolysis and tumor growth via increasing YY1 expression through sponging miR-769-3p in BC, offering a promising therapeutic target and prognostic biomarker for BC.
Other information
Title:

CircRNA circYY1 (hsa_circ_0101187) Modulates Cell Glycolysis and Malignancy Through Regulating YY1 Expression by Sponging miR-769-3p in Breast Cancer.

Journal: Cancer Manag Res
Published: 2021/2/20
PubMed ID: 33603460