circRNA basic information
circBase ID: -
Name: mmu_circ_TTC3
Synonym: -
Host Gene: mmu-miR-372-3p
 
 
 
Disease basic information
DO ID:
 2316
DO name: brain ischemia
Disease details: cerebral ischemia
Species: mouse
Species details: mouse
Sample type: tissue
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: TLR4
Associated microRNA: mmu-miR-372-3p
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 1
Description:

Thus, we conclude that circTTC3 regulates CIR injury and NSCs by the miR-372-3p/TLR4 axis in cerebral infarction. Our finding presents new insight into the mechanism by which circTTC3 modulates CIR injury and NSC dysfunction. CircTTC3, miR-372-3p, and TLR4 may serve as potential targets for the treatment of CIR injury during stroke.
Other information
Title:

Circular RNA TTC3 regulates cerebral ischemia-reperfusion injury and neural stem cells by miR-372-3p/TLR4 axis in cerebral infarction.

Journal: Stem Cell Res Ther
Published: 2021/2/14
PubMed ID: 33579365