circRNA basic information
circBase ID: hsa_circ_0119872
Name: -
Synonym: Circ_0119872
Host Gene: hsa-miR-622
 
 
 
Disease basic information
DO ID:
 6039
DO name: uveal melanoma
Disease details: uveal melanoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: SP6.5, VUP, OCM-1, 92_1, OCM-1A, MUM-2B, OM431
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: G3BP1
Associated microRNA: hsa-miR-622
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 1
Description:

Circ_0119872 may act as an oncogene in UM through a novel circ_0119872/miR-622/G3BP1 axis, activating the Wnt/beta-catenin and mTOR signalling pathways, which in turn may provide potential biomarkers and therapeutic targets for the management of UM.
Other information
Title:

Circ_0119872 promotes uveal melanoma development by regulating the miR-622/G3BP1 axis and downstream signalling pathways.

Journal: J Exp Clin Cancer Res
Published: 2021/2/14
PubMed ID: 33579337