circRNA basic information
circBase ID: -
Name: hsa_circ_USP36
Synonym: -
Host Gene: hsa-miR-20a-5p
 
 
 
Disease basic information
DO ID:
 1936
DO name: atherosclerosis
Disease details: atherosclerosis
Species: human
Species details: human
Sample type: cell line
Sample type details: HUVECs
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: ROCK2
Associated microRNA: hsa-miR-20a-5p
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 7
Description:

circUSP36 targeted miR_20a_5p to regulate the expression of ROCK2. On the whole, the present study demonstrates that, circUSP36 regulates ox_LDL_induced HUVEC injury and inflammation by modulating ROCK2 via competitively targeting miR_20a_5p.
Other information
Title:

CircUSP36 knockdown alleviates oxidized low_density lipoprotein_induced cell injury and inflammatory responses in human umbilical vein endothelial cells via the miR_20a_5p/ROCK2 axis.

Journal: Int J Mol Med
Published: 2021/2/13
PubMed ID: 33576448