circRNA basic information
circBase ID: -
Name: hsa_circ_HECTD1
Synonym: -
Host Gene: hsa-miR-296-3p
 
 
 
Disease basic information
DO ID:
 0060108
DO name: brain glioma
Disease details: glioma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: T98G, SHG44, U251, LN229, A172
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: SLC10A7
Associated microRNA: hsa-miR-296-3p
Biological function: Knockdown of circHECTD1 inhibited proliferation and invasion in vitro, and also reduced the growth of tumor and prolonged the prognosis in vivo.
Molecular mechanism: elevated the hsa-miR-296-3p expression
Survival: -
Supported No.:
 1
Description:

this study investigated a novel biomarker panel consisting of the circHECTD1/miR-296-3p/SLC10A7 axis, which is critical for glioma tumorigenesis and invasiveness and may represent a novel therapeutic target for intervening in glioma progression.
Other information
Title:

Circular RNA circHECTD1 facilitates glioma progression by regulating the miR-296-3p/SLC10A7 axis.

Journal: J Cell Physiol
Published: 2021/2/10
PubMed ID: 33561315