circRNA basic information
circBase ID: -
Name: hsa_circ_ANKIB1
Synonym: -
Host Gene: hsa-miR-217
 
 
 
Disease basic information
DO ID:
 3347
DO name: osteosarcoma
Disease details: osteosarcoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: U2OS, HOS
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: PAX3
Associated microRNA: hsa-miR-217
Biological function: Knockdown of circANKIB1 inhibited the progression of OS by reducing cell proliferation, migration, invasion, and tumor growth (in vivo), and inducing apoptosis
Molecular mechanism: regulating hsa-miR-217/PAX3 axis
Survival: -
Supported No.:
 3
Description:

Knockdown of circANKIB1 suppressed OS progression by upregulating miR-217 and downregulating PAX3, which might provide a novel insight into the pathogenesis of OS.
Other information
Title:

Circular RNA circANKIB1 promotes the progression of osteosarcoma by regulating miR-217/PAX3 axis.

Journal: J Bone Oncol
Published: 2021/2/9
PubMed ID: 33552886