circRNA basic information
circBase ID: hsa_circ_0000429
Name: -
Synonym: CircRNA_0000429
Host Gene: hsa-miR-1197
 
 
 
Disease basic information
DO ID:
 3908
DO name: lung non-small cell carcinoma
Disease details: non-small cell lung cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: Beas-2B, H2170, A549, SPC-A-1, PG49
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: MADD
Associated microRNA: hsa-miR-1197
Biological function: Knockdown of circ_0000429 significantly inhibited the cell proliferation, migration, and invasion of NSCLC cells in vitro
Molecular mechanism: acted as a sponge to absorb microRNA-1197 (hsa-miR-1197) and promoted MADD expression
Survival: -
Supported No.:
 1
Description:

circ_0000429 exhibited a carcinogenic role by sponging miR-1197 and regulating CMADD expression in NSCLC. These findings provided evidence for understanding the role of circ_0000429 in NSCLC tumorigenesis.
Other information
Title:

CircRNA_0000429 Regulates Development of NSCLC by Acting as a Sponge of miR-1197 to Control MADD.

Journal: Cancer Manag Res
Published: 2021/2/6
PubMed ID: 33542659