circRNA basic information
circBase ID: -
Name: hsa_circ_TOP2A
Synonym: -
Host Gene: hsa-miR-346
 
 
 
Disease basic information
DO ID:
 0060108
DO name: brain glioma
Disease details: glioma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: LN229, U251, U87MG
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: SUSD2
Associated microRNA: hsa-miR-346
Biological function: -
Molecular mechanism: miRNA sponge
Survival: poor
Supported No.:
 2
Description:

circ_TOP2A promoted GM proliferation and aggressiveness via miR_346/SUSD2 signaling, which is a potential prognostic biomarker and therapeutic target for GM.
Other information
Title:

Circ_TOP2A acts as a ceRNA for miR_346 and contributes to glioma progression via the modulation of sushi domain_containing 2.

Journal: Mol Med Rep
Published: 2021/2/5
PubMed ID: 33537815