circRNA basic information
circBase ID: -
Name: hsa_circ_EPSTI1
Synonym: hsa_circRNA_000479
Host Gene: hsa-miR-375, hsa-miR-409-3p, hsa-miR-515-5p
 
 
 
Disease basic information
DO ID:
 4362
DO name: cervical cancer
Disease details: cervical cancer
Species: human
Species details: human
Sample type: cell line, PDX
Sample type details: CaSki, HeLa, HcerEpic
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: SLC7A11
Associated microRNA: hsa-miR-375, hsa-miR-409-3p, hsa-miR-515-5p
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 2
Description:

our results revealed that circRNAs may also play very important roles in cervical cancer acting as miRNA sponges. We found that circEPSTI1-miR-375/409-3P/515-5p-SLC7A11 axis promotes the cervical cancer cell proliferation through a mechanism involving ceRNA.
Other information
Title:

Circular RNA circEPSTI1 accelerates cervical cancer progression via miR-375/409-3P/515-5p-SLC7A11 axis.

Journal: Aging (Albany NY)
Published: 2021/2/4
PubMed ID: 33534779