circRNA basic information
circBase ID: hsa_circ_0035483
Name: -
Synonym: Circ_0035483
Host Gene: hsa-miR-31-5p
 
 
 
Disease basic information
DO ID:
 4451
DO name: renal carcinoma
Disease details: renal carcinoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: 786-O, CaKi-1
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: HMGA1
Associated microRNA: hsa-miR-31-5p
Biological function: The inhibitory effects on RCC cell proliferation, migration, invasion, EMT and glycolysis were induced after circ_0035483 was downregulated
Molecular mechanism: regulating the hsa-miR-31-5p/HMGA1 axis
Survival: -
Supported No.:
 2
Description:

These findings clarified that the tumor-promoting function of circ_0035483 in RCC was partly achieved by regulating the miR-31-5p/HMGA1 axis.
Other information
Title:

Circ_0035483 Functions as a Tumor Promoter in Renal Cell Carcinoma via the miR-31-5p-Mediated HMGA1 Upregulation.

Journal: Cancer Manag Res
Published: 2021/2/4
PubMed ID: 33531839