circRNA basic information
circBase ID: -
Name: hsa_circ_GLIS3
Synonym: -
Host Gene: hsa-miR-644a
 
 
 
Disease basic information
DO ID:
 3908
DO name: lung non-small cell carcinoma
Disease details: non-small cell lung cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: A549, PC-9, H1299, H460, H1650
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: PTBP1
Associated microRNA: hsa-miR-644a
Biological function: promoted proliferation, migration and invasion and arrested apoptosis
Molecular mechanism: circGLIS3/hsa-miR-644a/PTBP1
Survival: poor
Supported No.:
 1
Description:

CircGLIS3 functions as an oncogene via sponging multiple tumor-suppressive miRNAs in NSCLC. A circGLIS3/miR-644a/PTBP1 positive feedback loop exists in the tumorigenesis and development of NSCLC.
Other information
Title:

A circGLIS3/miR-644a/PTBP1 positive feedback loop promotes the malignant biological progressions of non-small cell lung cancer.

Journal: Am J Cancer Res
Published: 2021/2/2
PubMed ID: 33520363