circRNA basic information
circBase ID: hsa_circ_0004277
Name: hsa_circ_WDR37
Synonym: -
Host Gene: -
 
 
 
Disease basic information
DO ID:
 684
DO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: HepG2, Bel-7402, MHCC97, Huh-7, SMMC-7721
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: -
Biological function: promote cells proliferation and migration
Molecular mechanism: inhibition of ZO-1 and promotion of EMT progressio
Survival: -
Supported No.:
 2
Description:

exosomal circ-0004277 from HCC cells stimulates EMT of peripheral cells through cellular communication to further promote the invasion of HCC into normal surrounding tissues.
Other information
Title:

Circular RNA hsa_circ_0004277 Stimulates Malignant Phenotype of Hepatocellular Carcinoma and Epithelial-Mesenchymal Transition of Peripheral Cells.

Journal: Front Cell Dev Biol
Published: 2021/1/30
PubMed ID: 33511111