circRNA basic information
circBase ID: -
Name: -
Synonym: CircRNA_141539
Host Gene: hsa-miR-4469
 
 
 
Disease basic information
DO ID:
 3748
DO name: esophagus squamous cell carcinoma
Disease details: esophageal squamous cell carcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: Kyse410, Kyse510, EC9706, ECA109 TE7, Het-1A
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
UP
Associated gene: CDK3
Associated microRNA: hsa-miR-4469
Biological function: circRNA_141539 overexpression promoted cell proliferation and invasion
Molecular mechanism: sponging hsa-miR-4469 and activating CDK3 expression
Survival: poor
Supported No.:
 1
Description:

circRNA_141539 served as an oncogenic factor in ESCC by sponging miR-4469 and activating CDK3 expression. circRNA_141539 may present as a novel diagnostic and prognostic biomarker and a therapeutic target for patients with ESCC.
Other information
Title:

circRNA_141539 can serve as an oncogenic factor in esophageal squamous cell carcinoma by sponging miR-4469 and activating CDK3 gene.

Journal: Aging (Albany NY)
Published: 2021/1/29
PubMed ID: 33504681