circRNA basic information
circBase ID: hsa_circ_0010235
Name: hsa_circ_ALDH4A1
Synonym: -
Host Gene: hsa-miR-433-3p
 
 
 
Disease basic information
DO ID:
 3908
DO name: lung non-small cell carcinoma
Disease details: non-small cell lung cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: H1299 , A549, H1581, H23
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: TIPRL
Associated microRNA: hsa-miR-433-3p
Biological function: Depletion of hsa_circ_0010235 or gain of miR-433-3p repressed proliferation and autophagy but promoted apoptosis in NSCLC cells
Molecular mechanism: Hsa_circ_0010235 sponged hsa-miR-433-3p to upregulate TIPRL expression, so as to affect NSCLC development.
Survival: -
Supported No.:
 4
Description:

Hsa_circ_0010235 knockdown suppressed NSCLC progression by regulating miR-433-3p/TIPRL axis, affording a novel mechanism of NSCLC progression.
Other information
Title:

Hsa_circ_0010235 functions as an oncogenic drive in non-small cell lung cancer by modulating miR-433-3p/TIPRL axis.

Journal: Cancer Cell Int
Published: 2021/1/27
PubMed ID: 33494763