circRNA basic information
circBase ID: -
Name: hsa_circ_NOLC1
Synonym: -
Host Gene: hsa-miR-647
 
 
 
Disease basic information
DO ID:
 10283
DO name: prostate cancer
Disease details: prostate cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: DU145, PC3, C4-2, LNCaP, 22RV1
circRNA-disease information
Detected method:
Q
S
Detected method confidence High
Expression pattern:
UP
Associated gene: PAQR4
Associated microRNA: hsa-miR-647
Biological function: promote cells proliferation and migration
Molecular mechanism: sponging hsa-miR-647, leading to the activation of PI3K/Akt pathway
Survival: -
Supported No.:
 1
Description:

CircNOLC1, elevated by transcription factor NF-kappaB, promotes PCa progression via a miR-647/PAQR4 axis, and circNOLC1 is a potential biomarker and target for PCa treatment.
Other information
Title:

Circular RNA CircNOLC1, Upregulated by NF-KappaB, Promotes the Progression of Prostate Cancer via miR-647/PAQR4 Axis.

Journal: Front Cell Dev Biol
Published: 2021/1/26
PubMed ID: 33490086