circRNA basic information
circBase ID: -
Name: hsa_circ_PUM1
Synonym: CircPUM1
Host Gene: hsa-miR-340-5p
 
 
 
Disease basic information
DO ID:
 4467
DO name: clear cell renal cell carcinoma
Disease details: clear cell renal cell carcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: Caki-2 (CL-0326), 786-O (CL-0010)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: FABP7
Associated microRNA: hsa-miR-340-5p
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 1
Description:

CircPUM1 upregulates FABP7 expression by competitively binding to miR-340-5p, and then activates the MEK/ERK pathway, thus promoting ccRCC progression.
Other information
Title:

Silencing of circular RNA PUM1 inhibits clear cell renal cell carcinoma progression through the miR-340-5p/FABP7 axis.

Journal: J Recept Signal Transduct Res
Published: 2021/1/22
PubMed ID: 33472512