circRNA basic information
circBase ID: -
Name: hsa_circ_EIF6
Synonym: -
Host Gene: hsa-miR-557
 
 
 
Disease basic information
DO ID:
 1793
DO name: pancreatic cancer
Disease details: pancreatic cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: Hs 766T, SW1990
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: SLC7A11/PI3K/AKT
Associated microRNA: hsa-miR-557
Biological function: Cell proliferation, migration and invasion were significantly restrained while cell apoptosis was induced with the silencing of circEIF6 in pancreatic cancer cells
Molecular mechanism: targeting hsa-miR-557/SLC7A11/PI3K/AKT signaling
Survival: -
Supported No.:
 1
Description:

CircEIF6 aggravated pancreatic cancer development through promoting cell proliferation, migration and invasion and suppressing cell apoptosis through targeting miR-557/SLC7A11/PI3K/AKT signaling.
Other information
Title:

Up-Regulation of circEIF6 Contributes to Pancreatic Cancer Development Through Targeting miR-557/SLC7A11/PI3K/AKT Signaling.

Journal: Cancer Manag Res
Published: 2021/1/21
PubMed ID: 33469368