circRNA basic information
circBase ID: -
Name: hsa_circ_NEK9
Synonym: -
Host Gene: hsa-miR-409-3p
 
 
 
Disease basic information
DO ID:
 10534
DO name: stomach cancer
Disease details: gastric cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: XGC-1 , MKN45 GC
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: MAP7
Associated microRNA: hsa-miR-409-3p
Biological function: CircNEK9 interference suppressed the proliferation and motility of GC cells.
Molecular mechanism: CircNEK9 silencing enhanced microRNA-409-3p (hsa-miR-409-3p) level through direct interaction
Survival: -
Supported No.:
 1
Description:

CircNEK9 accelerated the proliferation, migration, and invasion of GC cells through targeting miR-409-3p/MAP7 axis. Plasma exosomal circNEK9 promoted the migration and invasion of recipient GC cells.
Other information
Title:

Plasma Exosomal CircNEK9 Accelerates the Progression of Gastric Cancer via miR-409-3p/MAP7 Axis.

Journal: Dig Dis Sci
Published: 2021/1/16
PubMed ID: 33449227