circRNA basic information
circBase ID: hsa_circ_0030018
Name: hsa_circ_POSTN
Synonym: -
Host Gene: hsa-miR-1297
 
 
 
Disease basic information
DO ID:
 0060108
DO name: brain glioma
Disease details: glioma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: A172, U251, LN229, T98
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: RAB21
Associated microRNA: hsa-miR-1297
Biological function: The silence of hsa_circ_0030018 or overexpression of miR-1297 impeded cell proliferation, metastasis, and expedited cell apoptosis and cycle arrest in glioma cells.
Molecular mechanism: via sponging hsa-miR-1297, and hsa-miR-1297 suppressed glioma development via targeting RAB21
Survival: -
Supported No.:
 5
Description:

The hsa_circ_0030018 knockdown repressed glioma progression by mediating the miR-1297/RAB21 pathway, providing potential therapeutic targets for glioma treatment.
Other information
Title:

CircRNA hsa_circ_0030018 regulates the development of glioma via regulating the miR-1297/RAB21 axis.

Journal: Neoplasma
Published: 2021/1/15
PubMed ID: 33440987