circRNA basic information
circBase ID: -
Name: hsa_circ_ITCH
Synonym: cir-ITCH, circ-ITCH
Host Gene: hsa-miR-421
 
 
 
Disease basic information
DO ID:
 684
DO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: Huh7, Hep3B cells
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: CPEB3
Associated microRNA: hsa-miR-421
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 5
Description:

Lidocaine represses hepatocellular carcinoma cell proliferation, migration, and invasion and promotes apoptosis via regulating circ_ITCH/miR-421/CPEB3 axis, indicating a new insight into the mechanism of lidocaine in hepatocellular carcinoma.
Other information
Title:

Lidocaine Inhibits Hepatocellular Carcinoma Development by Modulating circ_ITCH/miR-421/CPEB3 Axis.

Journal: Dig Dis Sci
Published: 2021/1/13
PubMed ID: 33433806