circRNA basic information
circBase ID: -
Name: hsa_circ_PTPN22
Synonym: -
Host Gene: -
 
 
 
Disease basic information
DO ID:
 10534
DO name: stomach cancer
Disease details: gastric cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: MKN-1, MKN-45, BGC-823, MGC-803, SGC-7901, HGC-27, AGS
circRNA-disease information
Detected method:
Q
S
Detected method confidence High
Expression pattern:
UP
Associated gene: EMT pathway
Associated microRNA: -
Biological function: the downregulation of circPTPN22 could inhibit cell proliferation, migration, and invasion through the epithelial-mesenchymal transformation (EMT) pathway
Molecular mechanism: -
Survival: poor
Supported No.:
 1
Description:

CircPTPN22 can be used as a potential diagnostic and prognostic marker for GC and can inhibit cell proliferation and metastasis through the competitive binding of miRNA to inhibit the EMT pathway.
Other information
Title:

As a biomarker for gastric cancer, circPTPN22 regulates the progression of gastric cancer through the EMT pathway.

Journal: Cancer Cell Int
Published: 2021/1/13
PubMed ID: 33430866