circRNA basic information
circBase ID: -
Name: hsa_circ_PIP5K1A
Synonym: -
Host Gene: hsa-miR-515-5p
 
 
 
Disease basic information
DO ID:
 0060108
DO name: brain glioma
Disease details: glioma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: U87, TJ861, TJ905, U251, H4, A172
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: TCF12/PI3K/AKT pathway
Associated microRNA: hsa-miR-515-5p
Biological function: elevated glioma cell proliferation, invasion, and EMT and inhibited apoptosis
Molecular mechanism: upregulation of the TCF12/PI3K/AKT pathway by sponging hsa-miR-515-5p
Survival: -
Supported No.:
 1
Description:

CircPIP5K1A is a potential prognostic marker in glioma and regulates glioma evolvement by modulating the miR-515-5p-mediated TCF12/PI3K/AKT axis.
Other information
Title:

CircRNA PIP5K1A promotes the progression of glioma through upregulation of the TCF12/PI3K/AKT pathway by sponging miR-515-5p.

Journal: Cancer Cell Int
Published: 2021/1/9
PubMed ID: 33413401