circRNA basic information
circBase ID: -
Name: hsa_circ_WHSC1
Synonym: CircWHSC1
Host Gene: hsa-miR-142-3p
 
 
 
Disease basic information
DO ID:
 684
DO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: Hep3B, HuH7
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: HOXA1
Associated microRNA: hsa-miR-142-3p
Biological function: Knockdown of circWHSC1 suppressed HCC cell proliferation and metastasis in vitro and restrained tumorigenesis in vivo
Molecular mechanism: functioned as the sponge for hsa-miR-142-3p, which directly targeted HOXA1
Survival: -
Supported No.:
 1
Description:

CircWHSC1 played a tumour-promoting role in HCC by elevating HOXA1 through sponging miR-142-3p.
Other information
Title:

CircWHSC1 serves as an oncogene to promote hepatocellular carcinoma progression.

Journal: Eur J Clin Invest
Published: 2021/1/8
PubMed ID: 33410156