circRNA basic information
circBase ID: -
Name: hsa_circ_CCDC66
Synonym: -
Host Gene: hsa-miR-452-5p
 
 
 
Disease basic information
DO ID:
 4362
DO name: cervical cancer
Disease details: cervical cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: C33A, HT-3, HeLa, SiHa
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: REXO1
Associated microRNA: hsa-miR-452-5p
Biological function: Downregulated circ-CCDC66 inhibited cervical cancer cell proliferation, migration, and invasion.
Molecular mechanism: circ-CCDC66/hsa-miR-452-5p/REXO1 axis
Survival: -
Supported No.:
 1
Description:

Our results demonstrated the role of circ-CCDC66/miR-452-5p/REXO1 axis in cervical cancer progression, we might provide novel therapeutic targets for cervical cancer clinical intervention.
Other information
Title:

Circ-CCDC66 upregulates REXO1 expression to aggravate cervical cancer progression via restraining miR-452-5p.

Journal: Cancer Cell Int
Published: 2021/1/8
PubMed ID: 33407514