circRNA basic information
circBase ID: -
Name: hsa_circ_DNMT1
Synonym: -
Host Gene: hsa-miR-485-3p
 
 
 
Disease basic information
DO ID:
 1612
DO name: breast cancer
Disease details: breast cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: MCF-7, MDA-MB-231
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: ZEB1
Associated microRNA: hsa-miR-485-3p
Biological function: Circ-DNMT1 knockdown restrained cell colony formation, migration, and invasion and increased apoptosis
Molecular mechanism: Circ-DNMT1 silence reduced ZEB1 expression via regulating hsa-miR-485-3p
Survival: -
Supported No.:
 1
Description:

Circ-DNMT1 knockdown constrains breast cancer development via modulating miR-485-3p/ZEB1 axis.
Other information
Title:

CircRNA DNA methyltransferase 1 silence inhibits breast cancer development by regulating micoRNA-485-3p/zinc finger E-box binding homeobox 1 axis.

Journal: J Obstet Gynaecol Res
Published: 2021/1/7
PubMed ID: 33403756