circRNA basic information
circBase ID: -
Name: hsa_circ_RBM33
Synonym: -
Host Gene: hsa-miR-758-3p
 
 
 
Disease basic information
DO ID:
 4362
DO name: cervical cancer
Disease details: cervical cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: HeLa, SiHa
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: PUM2
Associated microRNA: hsa-miR-758-3p
Biological function: circRBM33 knockdown constrained tumor growth in vivo and cured CC cell proliferation, migration, invasion, glycolysis, and fostered CC cell apoptosis in in vitro
Molecular mechanism: sponged hsa-miR-758-3p to modulate PUM2 expression
Survival: -
Supported No.:
 1
Description:

CircRBM33 fostered CC advancement via absorbing miR-758-3p and upregulating PUM2, indicating that circRBM33 was a possible target for CC treatment.
Other information
Title:

Circular RNA RBM33 contributes to cervical cancer progression via modulation of the miR-758-3p/PUM2 axis.

Journal: J Mol Histol
Published: 2021/1/6
PubMed ID: 33398465