circRNA basic information
circBase ID: hsa_circ_0061012
Name: -
Synonym: Circ_0061012
Host Gene: hsa-miR-194-5p
 
 
 
Disease basic information
DO ID:
 8893
DO name: psoriasis
Disease details: psoriasis
Species: human
Species details: human
Sample type: tissue
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: GAB1
Associated microRNA: hsa-miR-194-5p
Biological function: contributes to IL-22-induced proliferation, migration and invasion
Molecular mechanism: through hsa-miR-194-5p/GAB1 axis
Survival: -
Supported No.:
 2
Description:

Circ_0061012 elevated the expression of GAB1 through sponging miR-194-5p in HaCaT cells. Circ_0061012 accelerated IL-22-induced proliferation and metastasis in HaCaT cells through enhancing GAB1 expression via sponging miR-194-5p in psoriasis.
Other information
Title:

Circ_0061012 contributes to IL-22-induced proliferation, migration and invasion in keratinocytes through miR-194-5p/GAB1 axis in psoriasis.

Journal: Biosci Rep
Published: 2021/1/5
PubMed ID: 33393621