circRNA basic information
circBase ID: -
Name: hsa_circ_BICD2
Synonym: -
Host Gene: hsa-miR-149-5p
 
 
 
Disease basic information
DO ID:
 50866
DO name: oral squamous cell carcinoma
Disease details: oral squamous cell carcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: SCC15, SCC25, CAL27, SCC4, SCC9
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: IGF2BP1
Associated microRNA: hsa-miR-149-5p
Biological function: circBICD2 knockdown repressed OSCC cell proliferation, migration, invasion, and glutaminolysis and increased apoptosis
Molecular mechanism: modulating hsa-miR-149-5p/IGF2BP1 axis
Survival: -
Supported No.:
 3
Description:

circBICD2 knockdown repressed OSCC cell proliferation, migration, invasion, and glutaminolysis and increased apoptosis via modulating miR-149-5p/IGF2BP1 axis, which might act as a potential target for OSCC treatment.
Other information
Title:

circBICD2 targets miR-149-5p/IGF2BP1 axis to regulate oral squamous cell carcinoma progression.

Journal: J Oral Pathol Med
Published: 2021/1/1
PubMed ID: 33382158