circRNA basic information
circBase ID: -
Name: hsa_circ_DHRS3
Synonym: circ_DHRS3
Host Gene: hsa-miR-183-5p
 
 
 
Disease basic information
DO ID:
 8398
DO name: osteoarthritis
Disease details: osteoarthritis
Species: human
Species details: human
Sample type: tissue
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: GREM1
Associated microRNA: hsa-miR-183-5p
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 2
Description:

Circ_DHRS3 mediated IL-1beta-administered chondrocyte proliferation, apoptosis and ECM degradation by positively regulating GREM1 expression via competitively targeting miR-183-5p.
Other information
Title:

Circ_DHRS3 positively regulates GREM1 expression by competitively targeting miR-183-5p to modulate IL-1beta-administered chondrocyte proliferation, apoptosis and ECM degradation.

Journal: Int Immunopharmacol
Published: 2020/12/29
PubMed ID: 33360372