circRNA basic information
circBase ID: hsa_circ_0006528
Name: -
Synonym: circ_0006528
Host Gene: hsa-miR-1236-3p
 
 
 
Disease basic information
DO ID:
 1612
DO name: breast cancer
Disease details: breast cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: MCF-7, MDA-MB-231
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: CHD4
Associated microRNA: hsa-miR-1236-3p
Biological function: promote cells proliferation, migration and invasion and Adriamycin Chemoresistance
Molecular mechanism: activate CHD4
Survival: poor
Supported No.:
 4
Description:

Downregulation of circ_0006528 restrained cell proliferation, migration, invasion, and drug resistance of ADM-resistant BCa cells through inhibiting CHD4 and inducing miR-1236-3p.
Other information
Title:

Knockdown of circ_0006528 Suppresses Cell Proliferation, Migration, Invasion, and Adriamycin Chemoresistance via Regulating the miR-1236-3p/CHD4 Axis in Breast Cancer.

Journal: J Surg Res
Published: 2020/12/18
PubMed ID: 33333383