circRNA basic information
circBase ID: hsa_circ_0026352
Name: hsa_circ_NR4A1
Synonym: -
Host Gene: -
 
 
 
Disease basic information
DO ID:
 1612
DO name: breast cancer
Disease details: breast cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: -
circRNA-disease information
Detected method:
Q
S
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: -
Biological function: inhibits proliferation and induces apoptosis
Molecular mechanism: The mRNA and protein expression of MEK, ERK, Bcl2 were significantly depressed, while the expression of BAD, caspase-3 were enhanced in the MCF-7 cells over-expressing circNR4A1.
Survival: -
Supported No.:
 1
Description:

Over-expression of circNR4A1 can inhibit cell proliferation and induce cell apoptosis in MCF-7 cells.
Other information
Title:

[Over-expression of circNR4A1/Hsa-circ-0026352 inhibits proliferation and induces apoptosis in MCF-7 cells].

Journal: Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi
Published: 2020/12/17
PubMed ID: 33325363