circRNA basic information
circBase ID: -
Name: -
Synonym: Circ_100984
Host Gene: hsa-miR-432-3p
 
 
 
Disease basic information
DO ID:
 11054
DO name: urinary bladder cancer
Disease details: bladder cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: HT-1376, HTB9, 253J, BT-B, Biu-87, 5637
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: c-Jun/YBX-1/beta-catenin feedback loop
Associated microRNA: hsa-miR-432-3p
Biological function: Silencing of circ_100984 and YBX-1 repressed BC tumor growth, migration, and invasion in vitro and in vivo.
Molecular mechanism: sponged hsa-miR-432-3p to indirectly regulate YBX-1 and epithelial-mesenchymal transition (EMT)-related molecules
Survival: -
Supported No.:
 1
Description:

circ_100984-miR-432-3p axis regulated c-Jun/YBX-1/beta-catenin feedback loop promotes BC progression, providing a potential therapeutic axis for BC progression.
Other information
Title:

circ_100984-miR-432-3p axis regulated c-Jun/YBX-1/beta-catenin feedback loop promotes bladder cancer progression.

Journal: Cancer Sci
Published: 2020/12/15
PubMed ID: 33314480