circRNA basic information
circBase ID: -
Name: hsa_circ_PLK1
Synonym: -
Host Gene: hsa-miR-4500
 
 
 
Disease basic information
DO ID:
 1612
DO name: breast cancer
Disease details: breast cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: BT549, HCC38
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: IGF
Associated microRNA: hsa-miR-4500
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 1
Description:

CircPLK1 silence inhibited BC cell growth, migration and invasion by regulating miR-4500/IGF1 axis, suggesting circPLK1/miR-4500/IGF axis might be a potential therapeutic target.
Other information
Title:

Circular RNA circPLK1 promotes breast cancer cell proliferation, migration and invasion by regulating miR-4500/IGF1 axis.

Journal: Cancer Cell Int
Published: 2020/12/11
PubMed ID: 33298061